2015.07-至今 安徽医科大学生命科学院，讲师
2010.09-2015.07 中国科学院生物物理研究所，研究生
2006.09-2010.07 中国科学技术大学，本科生
致癌信号通路高度活化是肿瘤发生、发展、转移及抗药性的重要原因。本课题组主要研究方向为肿瘤中的分子信号通路，致力于探索在常见肿瘤发展过程中发挥关键推动作用的信号通路。
1.
Ni Zegui#; Sun Pengli#; Zheng Jin#; Wu Mingqing#; Yang Congcong; Cheng
Maosheng; Yin Mingwei; Cui Chengying; Wang Guangxian; Yuan Lin; Gao Qian*; Li Yang*; JNK signaling promotes bladder cancer immune escape by regulating METTL3-mediated m6A modification of PD-L1 mRNA, Cancer Research, 2022, online. (期刊论文)
2. Gao Qian#; Yang Liuyang#; Shen Aolin; Li Yang; Li Yongxiang; Hu Shilian; Yang Runhuai; Wang Xiangting; Yao Xuebiao*; Shen Guodong*; A WNT7B-m(6)A-TCF7L2 positive feedback loop promotes gastric cancer progression and metastasis, Signal Transduction and Targeted Therapy, 2021, 6(1): 43. (期刊论文)
3. Gao Qian#;
Zheng Jin#; Ni Zegui; Sun Pengli; Yang Congcong; Cheng Maosheng; Wu
Mingqing; Zhang Xiuhong; Yuan Lin; Zhang Yingyin*; Li Yang*; The m(6)A
Methylation-Regulated AFF4 Promotes Self-Renewal of Bladder Cancer Stem
Cells, Stem Cells International, 2020, 2020: 8849218. (期刊论文)
4. Cheng Maosheng#; Sheng Lu#; Gao Qian#;
Xiong Qiuchan; Zhang Haojie; Wu Mingqing; Liang Yu; Zhu Fengyu; Zhang
Yingyin; Zhang Xiuhong; Yuan Quan; Li Yang*; The m(6)A methyltransferase
METTL3 promotes bladder cancer progression via AFF4/NF-kappa B/MYC
signaling network , Oncogene, 2019, 38(19): 3667-3680. (期刊论文)
5. Gao Qian#; Zhang Junfeng#; Wang Xiumei; Liu Ying; He Rongqiao; Liu Xingfeng; Wang Fei; Feng Jing; Yang Dongling; Wang Zhaoqing*; Meng Anming*; Yan Xiyun*; The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis, NATURE COMMUNICATIONS, 2017, 8. (期刊论文)
6. Gao Qian; Chen Xiongfei; Duan Hongxia; Wang Zhaoqing; Feng Jing; Yang Dongling; Song Lina; Zhou Ningxin*; Yan Xiyun*; FXYD6: a novel therapeutic target toward hepatocellular carcinoma, PROTEIN & CELL, 2014, 5(7): 532-543. (期刊论文)
1. 国家自然科学基金青年项目，WNT7B自分泌正反馈环路在胃癌转移中的作用，81802391，2019/01-2021/12,主持
2. 安徽省自然科学基金青年项目，甲状腺癌新型分子靶标及其机制的研究，1808085QH266，2018/07–2020/06,主持
