个人简介:
2020.12-至今 安徽医科大学,bat36中国官方网站,讲师
2018.04-2020.04 美国圣路易斯华盛顿大学医学院,博士后
2014.03-2017.10 上海交通大学,博士
2014.03-2019.12 华东师范大学,硕士
个人荣誉及学术任职
2022年 安徽省第五届青年教师教学竞赛,三等奖
2022年 安徽省高等医学教育合作委员会“课程思政”案例 征集比赛,优秀奖
1. Chen Y, He A. Isolation and Differentiation of Adipocyte Precursors Derived from Neonatal Murine Brown Adipose Tissue. Methods Mol Biol. 2023; 2662:25-31.
2. Chen Y#, Tang C#, Zhang M#, Huang W, Xu Y, Sun H, Yang F, Song L, Wang H, Mu L, Li MH, Zheng W, Miao Y, Ding LX, Li BS, Shen S, Liu SL, Li H, Zhu Z, Chen H, Tang ZH, Chen J, Hong D, Chen H*, Duan C*, Zhou B*. Blocking ATM-dependent NF-κB pathway overcomes niche protection and improves chemotherapy response in acute lymphoblastic leukemia. Leukemia. 2019 Oct;33(10):2365-2378.
3. Li Q, Chen Y, Zhang D, Grossman J, Li L, Khurana N, Jiang H, Grierson PM, Herndon J, DeNardo DG, Challen GA, Liu J, Ruzinova MB, Fields RC, Lim KH. IRAK4 mediates colitis-induced tumorigenesis and chemoresistance in colorectal cancer. JCI Insight. 2019 Oct 3;4(19): e130867.
4. Tang C, Li MH, Chen YL, Sun HY, Liu SL, Zheng WW, Zhang MY, Li H, Fu W, Zhang WJ, Liang AB, Tang ZH, Hong DL, Zhou BS*, Duan CW*. Chemotherapy-induced niche perturbs hematopoietic reconstitution in B-cell acute lymphoblastic leukemia. J Exp Clin Cancer Res. 2018 Aug 29;37(1):204.
5. Chen Y, Lv J, Li K, Xu J, Li M, Zhang W, Pang X*. Sporoderm-Broken Spores of Ganoderma lucidum Inhibit the Growth of Lung Cancer: Involvement of the Akt/mTOR Signaling Pathway. Nutr Cancer. 2016 Oct;68(7):1151-60.
6. He A, Dean JM, Lu D, Chen Y, Lodhi IJ*. Hepatic peroxisomal β-oxidation suppresses lipophagy via RPTOR acetylation and MTOR activation. Autophagy. 2020 Sep;16(9):1727-1728.
7. He A#, Chen X#, Tan M#, Chen Y#, Lu D#, Zhang X, Dean JM, Razani B, Lodhi IJ*. Acetyl-CoA Derived from Hepatic Peroxisomal β-Oxidation Inhibits Autophagy and Promotes Steatosis via mTORC1 Activation. Mol Cell. 2020 Jul 2;79(1):30-42. e4.
8. Park H#, He A#, Tan M#, Johnson JM, Dean JM#, Pietka TA, Chen Y#, Zhang X, Hsu FF#, Razani B, Funai K, Lodhi IJ*. Peroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission. J Clin Invest. 2019 Feb 1;129(2):694-711.
1. 安徽省自然科学基金,Trim22介导胰腺癌ERK抑制剂治疗耐受的分子机制研究,2022/01-2023/12, 主持;
2. 安徽省高校自然科学基金,ERK抑制剂诱导胰腺癌耐药相关基因Trim22上调的分子机制研究,2021/10-2023/10, 主持;
3. 安徽医科大学自然科学基金,胰腺癌对ERK抑制剂耐受的分子机制研究,2022/01-2023/12, 主持;
4. 安徽医科大学引进人才科研启动项目, 2020/12-2025/12, 主持.