个人经历
2022.07 - 现在 bat36中国官方网站，校聘副教授
2016.09 - 2022.06 中国科学技术大学，硕博连读，博士
2012.09 - 2016.07 西北大学，学士
个人荣誉
2018年度 光华奖学金
2016-2022年度 中国科学技术大学研究生一等学业奖学金
本课题组主要利用核酸工具搭建诊断和治疗的新系统以实现生物学和医学领域的应用，包括：1、基于核酸适配体的靶向递送；2、基于核酸分子器件的靶向蛋白质降解。
1.Yi Du, Qiwei Wang, Lili Shi, Tao Li. G-quadruplex-Proximized Aptamers (G4PA) Efficiently Targeting to Cell-Surface Transferrin Receptors for Targeted Cargo Delivery. Nano.Lett., 2022, 15, 6328-6333.
2.Yi Du#, Pai Peng#, Tao Li*. DNA Logic Operations in Living Cells Utilizing Lysosome-Recognizing Framework Nucleic Acid Nanodevices for Subcellular Imaging. ACS Nano 2019, 13, 5778-5784.
3. Yi Du, Pai Peng, Tao Li*. Logic circuit controlled multi-responsive branched DNA scaffolds. Chem. Commun. 2018, 54, 6132–6135.
4. Pai Peng#, Yi Du#, Jiao Zheng, Huihui Wang, Tao Li*. Reconfigurable Bioinspired Framework Nucleic Acid Nanoplatform Dynamically Manipulated in Living Cells for Subcellular Imaging. Angew. Chem. Int. Ed. 2019, 58, 1648–1653.
5.Jiao Zheng, Yi Du, Huihui Wang, Pai Peng, Lili Shi, Tao Li*. Ultrastable Bimolecular G-quadruplexes Programmed DNA Nanoassemblies for Reconfigurable Biomimetic DNAzymes. ACS Nano 2019, 13, 11947–11954.
6. Pai Peng, Yi Du, Tao Li*. DNA Nanodevices Monitored with Fluorogenic Looped-Out 2-Aminopurine. Analyst 2018, 143, 1268–1273.
7. Pai Peng, Yi Du, Yudie Sun, Shuangna Liu, Lan Mi, Tao Li*. Probing Propeller-Like Loops of DNA G-quadruplexes with Looped-Out 2-Aminopurine for Label-Free Switchable Molecular Sensing. Analyst 2018, 143, 3814–3820.
8.Lili Shi, Pai Peng, Yi Du, Tao Li*. Programmable I-Motif DNA Folding Topology for a pH-Switched Reversible Molecular Sensing Device. Nucleic Acids Res. 2017, 45, 4306–4314.
9.Huihui Wang, Pai Peng, Qiwei Wang, Yi Du, Zhijin Tian, Tao Li*. Environment-Recognizing DNA-Computation Circuits for the Intracellular Transport of Molecular Payloads for mRNA Imaging. Angew. Chem. Int. Ed. 2020, 59, 6099–6107.
10. Pai Peng, Qiwei Wang, Yi Du, Huihui Wang, Lili Shi, Tao Li*. Extracellular Ion-Responsive Logic Sensors Utilizing DNA Dimeric Nanoassemblies on Cell Surface and Application to Boosting AS1411 Internalization. Anal. Chem. 2020, 92, 9273–9280.
