个人经历
2021.01-至今 安徽医科大学,bat36中国官方网站,副教授
2020.09-2020.11 中国科学院大学重庆学院,bat36中国官方网站,项目副研究员
2015.09-2020.07 中国科学技术大学,博士(导师:李涛教授)
2011.09-2015.07 河南师范大学,学士
个人荣誉
2020.05 中国科学院院长奖优秀奖
2019.04 《第八届化学与材料科学研究生中文学术年会暨第二届中国科大化材学院-科教融合学院学术年会》中获二等奖
2017-2019 连续三年获得中国科学技术大学博士研究生学业一等奖学金
2017.11 硕士研究生国家奖学金
2015-2016 连续两年获得中国科学技术大学硕士研究生学业一等奖学金
1. 基于框架核酸的活体原位传感及成像技术研究;
2. 基于DNA的重大疾病诊断新策略和新技术研究;
3. 基于结构性与功能性DNA纳米技术的逻辑门及逻辑电路研究;
1. Gong H, Dai Q*, Pai Peng*. Cell-Membrane-Anchored DNA Logic-Gated Nanoassemblies for In Situ Extracellular Bioimaging. ACS Appl Mater Interfaces. 2022 Sep 28;14(38):43026-43034.
2. Pai Peng#, Yi Du#, Jiao Zheng, Huihui Wang, Tao Li*. Reconfigurable Bioinspired Framework Nucleic Acid Nanoplatform Dynamically Manipulated in Living Cells for Subcellular Imaging. Angew. Chem. Int. Ed. 2019, 58, 1648–1653.
3. Pai Peng#, Lili Shi#, Huihui Wang, Tao Li*. A DNA nanoswitch-controlled reversible nanosensor. Nucleic Acids Res. 2017, 45, 541–546.
4. Pai Peng, Qiwei Wang, Yi Du, Huihui Wang, Tao Li*. Extracellular Ion-Responsive Logic Sensors Utilizing DNA Dimeric Nanoassemblies on Cell Surface and Application to Boosting AS1411 Internalization. Anal. Chem., 2020, 92, 13, 9273–9280.
5. Pai Peng, Yi Du, Yudie Sun, Shuangna Liu, Lan Mi, Tao Li*. Probing Propeller-[like] Loops of DNA G-quadruplexes with Looped-Out 2-Aminopurine for Label-Free Switchable Molecular Sensing. Analyst 2018, 143, 3814–3820.
6. Pai Peng, Yi Du, Tao Li*. DNA Nanodevices Monitored with Fluorogenic Looped-Out 2-Aminopurine. Analyst 2018, 143, 1268–1273.
7. Lili Shi#, Pai Peng#, Jiao Zheng, Zhijin Tian, Huihui Wang and Tao Li*. I-Motif/miniduplex hybrid structures bind benzothiazole dyes with unprecedented efficiencies: a generic light-up system for label-free DNA nanoassemblies and bioimaging. Nucleic Acids Res. 2020, 48, 1681–1690.
8. Yi Du#, Pai Peng#, Tao Li*. DNA Logic Operations in Living Cells Utilizing Lysosome-Recognizing Framework Nucleic Acid Nanodevices for Subcellular Imaging. ACS Nano 2019, 13, 5778-5784.
9. Huihui Wang, Pai Peng, Qiwei Wang, Yi Du, Zhijin Tian, and Tao Li*. Environment‐Recognizing DNA Computation Circuit‐Controlled Intracellular Transport of Molecular Payloads for mRNA Imaging. Angew. Chem. Int. Ed. 2020, 59, 6099-6107.
10. Yi Du, Pai Peng, Tao Li*. Logic circuit controlled multi-responsive branched DNA scaffolds. Chem. Commun. 2018, 54, 6132–6135.
11. Yudie Sun, Pai Peng, Ruiyan Guo, Huihui Wang, Tao Li*. Exonuclease III-boosted cascade reactions for ultrasensitive SERS detection of nucleic acids. Biosens. Bioelectron. 2018, 104, 32–38.
12. Shuangna Liu, Pai Peng, Huihui Wang, Lili Shi*, Tao Li*. Thioflavin T Binds Dimeric Parallel-Stranded GA-Containing Non-G-quadruplex DNAs. A General Approach to Lighting up Double-stranded Scaffolds. Nucleic Acids Res. 2017, 45, 12080–12089.
13. Lili Shi, Pai Peng, Yi Du, Tao Li*. Programmable I-Motif DNA Folding Topology for a pH-Switched Reversible Molecular Sensing Device. Nucleic Acids Res. 2017, 45, 4306–4314.
14. Huihui Wang, Pai Peng, Shuangna Liu, Tao Li*. Thioflavin T behaves as an efficient fluorescent ligand for label-free ATP aptasensor. Anal. Bioanal. Chem. 2016, 408, 7927–7934.
15. Jiao Zheng, Yi Du, Huihui Wang, Pai Peng, Lili Shi, Tao Li*. Unprecedentedly Stable Biomolecular G-Quadruplexes Programmed DNA Nanoassemblies for Reconfigurable Biomimetic DNAzymes. ACS Nano. 2019, 13, 11947-11954
1. 国家自然科学基金,青年项目,主持人,项目批准号:22104002,项目起止年月:2022.01-2024.12。
2. 国家自然科学基金,面上项目,参与人,项目批准号:21874124,项目起止年月:2019.01-2022.12。
3. 安徽医科大学人才科研启动项目,主持人,项目批准号:0801034201,项目起止年月:2021.01-2026.01。